Yinfa Yan Selected Research

EBI-907

2/2016	Discovery of EBI-907: A highly potent and orally active B-Raf(V600E) inhibitor for the treatment of melanoma and associated cancers.
1/2016	EBI-907, a novel BRAF(V600E) inhibitor, has potent oral anti-tumor activity and a broad kinase selectivity profile.

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Yinfa Yan Research Topics

Disease

5	Neoplasms (Cancer) 01/2022 - 01/2016
2	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2022 - 01/2021
2	Colorectal Neoplasms (Colorectal Cancer) 10/2021 - 01/2016
1	Autoimmune Diseases (Autoimmune Disease) 01/2022
1	Bites and Stings (Sting) 01/2022
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2022
1	Inflammation (Inflammations) 01/2021
1	Breast Neoplasms (Breast Cancer) 01/2021
1	Neoplasm Metastasis (Metastasis) 01/2021
1	Melanoma (Melanoma, Malignant) 02/2016
1	Alzheimer Disease (Alzheimer's Disease) 09/2011
1	Central Nervous System Diseases (CNS Diseases) 11/2010
1	Schizophrenia (Dementia Praecox) 05/2010

Drug/Important Bio-Agent (IBA)

3	CytokinesIBA 01/2022 - 01/2021
2	LigandsIBA 01/2022 - 11/2010
2	Interferon Type IIBA 01/2022 - 01/2022
2	Interleukin-6 (Interleukin 6)IBA 01/2022 - 01/2021
2	Interleukin-17 (Interleukin 17)IBA 10/2021 - 01/2021
2	EBI-907IBA 02/2016 - 01/2016
1	Janus Kinase InhibitorsIBA 01/2022
1	ADU-S100IBA 01/2022
1	cyclic guanosine monophosphate-adenosine monophosphateIBA 01/2022
1	Neoplasm Antigens (Tumor Antigens)IBA 01/2022
1	InterferonsIBA 01/2022
1	NucleotidesIBA 01/2022
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2022
1	Interleukin-12 (IL 12)IBA 01/2022
1	Janus KinasesIBA 01/2022
1	TYK2 Kinase (Tyrosine Kinase 2)IBA 01/2022
1	Interleukin-23 (Interleukin 23)IBA 01/2022
1	compound 17IBA 10/2021
1	Petrolatum (Vaseline)FDA Link 01/2021
1	Imiquimod (Aldara)FDA LinkGeneric 01/2021
1	Adenosine (Adenocard)FDA LinkGeneric 01/2021
1	Phosphotransferases (Kinase)IBA 01/2016
1	VemurafenibIBA 01/2016
1	Amyloid (Amyloid Fibrils)IBA 09/2011
1	Peptide Hydrolases (Proteases)FDA Link 09/2011
1	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 09/2011
1	serotonin 6 receptorIBA 11/2010
1	Dopamine (Intropin)FDA LinkGeneric 05/2010
1	Serotonin Receptor Agonists (Serotonin Receptor Agonist)IBA 05/2010

Therapy/Procedure

2	Therapeutics 01/2021 - 01/2021